William R Wilcox Selected Research

Carcinoma (Carcinomatosis)

7/2010

NF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cells.

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William R Wilcox Research Topics

Disease

28	Fabry Disease (Fabry's Disease) 11/2023 - 02/2003
10	Achondroplasia 04/2024 - 11/2005
5	Neoplasms (Cancer) 03/2016 - 08/2007
4	Chondrosarcoma 08/2007 - 11/2005
3	Inborn Genetic Diseases (Disease, Hereditary) 05/2015 - 08/2006
3	Dwarfism 04/2015 - 07/2010
3	Multiple Myeloma 01/2014 - 06/2009
2	Body Weight (Weight, Body) 04/2024 - 01/2007
2	Injection Site Reaction 01/2024 - 10/2023
2	Abdominal Pain (Pain, Abdominal) 12/2020 - 01/2018
2	Diarrhea 12/2020 - 01/2018
2	Stroke (Strokes) 01/2016 - 05/2015
2	Proteinuria 01/2007 - 08/2003
1	Gastroenteritis 01/2024
1	Skull Fractures (Skull Fracture) 01/2024
1	Otitis Media 01/2024
1	Paramyxoviridae Infections (Parainfluenza) 01/2024
1	Autistic Disorder (Autism) 01/2024
1	Bronchiolitis 01/2024
1	Pneumonia (Pneumonitis) 01/2024
1	Vomiting 01/2024
1	Absence Epilepsy (Childhood Absence Epilepsy) 01/2024
1	Erythema 01/2024
1	Sudden Infant Death (SID) 01/2024
1	Disease Progression 01/2023
1	COVID-19 12/2020
1	Infections 12/2020
1	X-Linked Genetic Diseases 01/2020
1	Hypophosphatasia 01/2019
1	Failure to Thrive 01/2019
1	Congenital Abnormalities (Deformity) 01/2019
1	Respiratory Insufficiency (Respiratory Failure) 01/2019
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2016
1	Hypotension (Low Blood Pressure) 12/2015
1	Schneckenbecken dysplasia 10/2015
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 05/2015
1	Renal Insufficiency (Renal Failure) 05/2015
1	Thanatophoric Dysplasia (Dwarfism, Thanatophoric) 11/2014
1	Polydactyly (Polydactylism) 08/2014
1	Triphalangeal Thumb 08/2014
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2014
1	Fibrochondrogenesis 11/2010
1	Carcinoma (Carcinomatosis) 07/2010
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 05/2010
1	Gerodermia osteodysplastica 12/2008
1	Lymphoid Leukemia 12/2007
1	HEM dysplasia 04/2003

Drug/Important Bio-Agent (IBA)

10	GalactosidasesIBA 01/2023 - 03/2012
9	agalsidase beta FDA Link 11/2023 - 01/2007
8	GlycosphingolipidsIBA 01/2023 - 08/2006
7	vosoritideIBA 04/2024 - 04/2015
7	alpha-Galactosidase (Beano)IBA 05/2010 - 02/2003
6	globotriaosylceramide (globotriosylceramide)IBA 01/2023 - 09/2005
6	Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA 12/2021 - 06/2009
4	C-Type Natriuretic Peptide (Peptide, C-Type Natriuretic)IBA 01/2024 - 04/2015
4	migalastatIBA 01/2023 - 08/2016
4	EnzymesIBA 05/2015 - 09/2005
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2012 - 07/2010
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 12/2007 - 03/2007
2	GlycolipidsIBA 12/2020 - 07/2009
2	LipidsIBA 08/2003 - 05/2002
1	venglustatIBA 01/2023
1	ceramide glucosyltransferaseIBA 01/2023
1	AngiotensinsIBA 12/2020
1	ReninIBA 12/2020
1	CalciumIBA 01/2019
1	Inositol (Myoinositol)IBA 10/2015
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 10/2015
1	PolyphosphatesIBA 10/2015
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 04/2015
1	Neprilysin (Neutral Endopeptidase)IBA 04/2015
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 04/2015
1	9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA 08/2014
1	Tuberculin (PPD)IBA 08/2014
1	Phosphotransferases (Kinase)IBA 01/2014
1	Transcription Factors (Transcription Factor)IBA 01/2014
1	Tyrosine (L-Tyrosine)FDA Link 01/2014
1	Collagen Type XIIBA 11/2010
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 11/2010
1	ChemokinesIBA 07/2010
1	4,4,',4'',4'''- (carbonylbis(imino- 5,1,3- benzenetriylbis(carbonylimino)))tetrakis(benzene- 1,3- disulfonate)IBA 07/2010
1	VitaminsIBA 06/2010
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 06/2009
1	Golgi Matrix ProteinsIBA 12/2008
1	Proteins (Proteins, Gene)FDA Link 12/2007
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 08/2007
1	Fibroblast Growth Factor 1 (FGF-1)IBA 03/2007
1	Protein Kinase CIBA 02/2007
1	bisindolylmaleimide IIBA 02/2007
1	Mitogen-Activated Protein KinasesIBA 11/2005
1	Natriuretic PeptidesIBA 11/2005
1	CreatinineIBA 08/2003
1	ChromatinIBA 04/2003

Therapy/Procedure

15	Therapeutics 04/2024 - 02/2003
11	Enzyme Replacement Therapy 01/2023 - 02/2003
1	Mechanical Ventilators (Ventilator) 01/2019
1	Precision Medicine 03/2016
1	Heart Transplantation (Grafting, Heart) 01/2016
1	Renal Dialysis (Hemodialysis) 01/2016
1	Intravenous Infusions 01/2007